Bioactive Small Molecules
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Filtered Search Results
Lkt Laboratories Etoposide Phosphate, ≥98%, 25MG
Epipodophyllotoxin derivative; topoisomerase II inhibitor. CAS: 117091-64-2 . Additional sizes available upon request. Ships from Saint Paul, MN.
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Selleck Chemical LLC Apilimod mesylate S0785-100MG
Apilimod mesylate is a potent and orally-available inhibitor of the cytokines interleukin-12 (IL-12) and interleukin-23 (IL-23) with the potential to treat certain autoimmune and inflammatory diseases Apilimod mesylate (STA-5326 mesylate) inhibits IL-12 with IC50 of 1 nM 1 nM and 2 nM in IFN- /SAC-stimulated human PBMCs human monocytes and mouse PBMCs respectively Apilimod mesylate (STA-5326 mesylate) is also a cell permeable small molecule that specifically inhibits PIKfyve with IC50 of 14 nM
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Medchemexpress LLC 8,11,14-Eicosatrienamide, N-(2-hydroxyethyl)-, (8Z,11Z,14Z)- | 150314-34-4 | MFCD00674172 | ≥99.0% | 349.55 g·mol⁻1 | C22H39NO2 | 5 MG
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Dihomo-γ-linolenoyl ethanolamide is an endogenous N-acylethanolamine that acts as a cannabinoid (CB) receptor agonist. It binds human recombinant CB1 and CB2 receptors with reported Ki values of 857 nM and 598 nM, respectively. The compound is provided as a high-purity research reagent for biochemical and pharmacology studies.
- Acts as a cannabinoid receptor agonist (CB1 and CB2).
- Reported Ki values: CB1 857 nM, CB2 598 nM.
- High purity (≥99.0% by HPLC).
- Molecular formula C22H39NO2; molecular weight 349.55 g·mol⁻1.
- Available in small-scale research quantities, e.g., 5 mg.
- Suitable for endocannabinoid signaling and receptor pharmacology research.
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eMolecules 1144035-53-9 | Medchem Express | PF-8380 | 5mg | 446262820 | HY-13344 | MFCD20527274 | 478.33 | C22H21Cl2N3O5
Ambeed | 6-Benzyl-24-dichloro-5H-pyrrolo[34-d]pyrimidin-7(6H)-one | 100mg | 600846205 | A711470 | 1207368-82-8 | MFCD23704678 | 294.140 | C13H9Cl2N3O
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Medchemexpress LLC 2-Bromothiazole | 3034-53-5 | 164.03 | 50 G
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2-Bromothiazole is a biochemical reagent suitable for life science research. It serves as an organic compound or biological material and is intended for research purposes only. This aryl halide can be N-arylated with 5- and 7-azaindoles, and its copper-catalyzed cyanation yields 2-cyanothiazole.
- Used as a biological material or organic compound for life science research
- Intended for research purposes only
- Functions as an aryl halide for N-arylation with 5- and 7-azaindoles
- Can undergo copper-catalyzed cyanation to produce 2-cyanothiazole
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Medchemexpress LLC HY-15245 10mg , GSK2636771 CAS:1372540-25-4 Purity:>98%
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HY-15245 10mg GSK2636771 CAS: 1372540-25-4 GSK2636771 is a potent, selective and orally bioavailable inhibitor of PI3Kβ with a Ki of 0.89 nM and an IC50 of 5.2 nM, showing 900-fold selectivity over p110α and p110γ, and 10-fold selectivity over p110δ isoforms. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Cayman Chemical DCPIB, Purity: ≥98%, CAS: 82749-70-0, 5 mg
A VRAC inhibitor; inhibits ICl,swell in bovine pulmonary artery endothelial cells (IC50 = 4.1 µM); inhibits LRRC8A (IC50 = 20.9 µM) and inhibits sphingosine-1-phosphate-induced cGAMP uptake by LRRC8A in TIME cells at 20 µM; inhibits K2P18.1/TRESK, K2P3.1/TASK1, and K2P9.1/TASK3 in COS-7 cells expressing the human channels (IC50s = 0.14, 0.95, and 50.72 µM, respectively); activates K2P2.1/TREK1 and K2P4.1/TRAAK channels in COS-7 cells expressing the human channels at 10 µM; intracisternal administration reduces infarct area and neurological deficit scores in a rat model of cerebral ischemia induced by MCAO at 20 µg/kg
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TARGETMOL CHEMICALS INC BMS-813160 5MG
Also available in 1 mg 10 mg 25 mg 50 mg 100 mg 500 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. BMS-813160 is the first dual CCR2/CCR5 antagonist to enter Clinical development for cardiovascular. purity: 99%
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Selleck Chemical LLC KAN0438757 S0400-5MG
KAN0438757 is a potent and selective inhibitor of the metabolic kinase PFKFB3 (6-Phosphofructo-2-Kinase/Fructose-2 6-Biphosphatase 3) with IC50 of 0 19 M and 3 6 M for PFKFB3 and PFKFB4 respectively
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Cayman Chemical 1,3-Dilinoleoyl-2-Stearoyl Glycerol, Purity: ≥98%, CAS: 2190-18-3, 5 mg
A triacylglycerol; has been found in soybean oil as well as transitional and mature human milk
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Medchemexpress LLC Butanoic acid, 4-[[(1,1-dimethylethoxy)carbonyl]amino]-2-[[(9H-fluoren-9-ylmethoxy)carbonyl]amino]-, (2S)- | 125238-99-5 | 440.49 | 1 ML
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Fmoc-Dab(Boc)-OH is an amino acid derivative with an Fmoc protecting group. It can be used to synthesize somatostatin analogs that inhibit neointima formation induced by balloon injury in rats without altering growth hormone release, and can also be used for the synthesis of peptides.
- Amino acid derivative with an Fmoc protecting group
- Synthesizes somatostatin analogs
- Inhibits neointima formation induced by balloon injury in rats
- Does not alter growth hormone release
- Used for peptide synthesis
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Medchemexpress LLC P 22077 | 1247819-59-5 | 98.4% | 315.32 | 10 MM * 1 ML
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P 22077 is a cell-permeable ubiquitin-specific protease 7 (USP7) inhibitor with an EC50 of 8.01 μM. It also inhibits USP47 with an EC50 of 8.74 μM.
- Inhibits USP7 and DUB USP47 with EC50s of 8.01 μM and 8.74 μM
- Inhibits a smaller subset of DUBs at concentrations of 15-45 μM
- Reduces cell viability of neuroblastoma (NB) cells at 0-20 μM
- Increases p53 activity and induces apoptosis in p53 wild-type and HDM2-expressing NB cells
- Enhances cytotoxic effect of Doxorubicin and Etoposide on NB cells
- Shows potent antitumor activities in an xenograft mouse model
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Lkt Laboratories S-Sulforaphane, ≥97%, 10MG
Synthetic antioxidant that induces phase II enzyme activity. CAS: 155320-20-0. Additional sizes available upon request. Ships from Saint Paul, MN.
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Lkt Laboratories Baccatin III, ≥98%, 25MG
Diterpene found in Taxus, used to synthesize taxol. CAS: 27548-93-2. Additional sizes available upon request. Ships from Saint Paul, MN.
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Lkt Laboratories (E,Z)-4-Hydroxytamoxifen, ≥97%, 25MG
Selective estrogen receptor modulator. CAS: 68392-35-8. Additional sizes available upon request. Ships from Saint Paul, MN.
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